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Chapter 18-6. Somatosensory System

Recommended reading: 【Biology】 Chapter 18. Sensory System


1. Overview

2. Ascending pathways

3. Type 1. Mechanoreceptors)

4. Type 2. Nociceptors (pain receptors)



1. Overview

⑴ Skin

① An outer covering that wraps the body surface

② The largest organ in our body

Component 1. Epidermal layer: Rich in keratin. Impermeable

Component 2. Dermal layer: Rich in collagen fibers, water, electrolytes, proteins, and glycosaminoglycans

⑵ The five cutaneous senses: pain, pressure, touch, cold, warmth


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Figure 1. Cutaneous receptors for the five skin senses]


① Pain: The sense of feeling pain

○ Involves nerve endings in the dermis (free endings)

○ Has the greatest number of receptors

② Pressure: The sense of pressure

○ Involves Merkel’s disks in the epidermis

○ Involves Pacinian corpuscles (Pacinian corpuscle) in the dermis

○ Pacinian corpuscles contain abundant collagen, showing characteristics of phasic receptors

○ If connective tissue is removed from Pacinian corpuscles, they show characteristics of tonic receptors

③ Touch: The sense felt when something makes contact

○ Involves Meissner’s corpuscles in the epidermis to dermis

○ Many at the lips and fingertips; fewer at the thigh and buttocks

○ More sensitive to hair than to skin

④ Cold: The sense of coldness

○ Involves the endbulb of Krause in the dermis

⑤ Warmth: The sense of warmth

○ Involves Ruffini corpuscles in the dermis

○ Has the fewest receptors among the five senses

⑥ Comparison of receptor numbers: pain>pressure>touch>cold>warmth



2. Ascending pathways

⑴ Most spinal ascending pathways decussate in the medulla

⑵ Sensory information from the skin, joints, and muscles

① 1st. Ascends ipsilaterally in the spinal cord, then decussates in the medulla

② 2nd. Transmitted along the dorsal column medial lemniscus pathway

③ 3rd. Projects to the primary sensory cortex via the ventrobasal complex, a specific sensory nucleus of the thalamus

⑶ Pain, temperature, crude or light touch

① 1st. Transmitted along the anterolateral system

○ 1st - 1st. Pain is transmitted via the lateral spinothalamic tract within the anterolateral system

○ 1st - 2nd. Temperature is transmitted via the anterior spinothalamic tract within the anterolateral system

② 2nd. Decussates in the spinal cord


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Figure 2. Pathways of cutaneous sensation]


3. Type 1. Mechanoreceptors


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Figure 3. Major structures along the sensory pathway


⑴ VPL (ventral posterolateral nucleus): Delivers sensory information to Brodmann areas 1, 2, and 3

⑵ Somatosensory cortex: Parietal lobe; Brodmann areas 1, 2, 3, and 5

① Postcentral gyrus: Primary somatosensory cortex

② Superior parietal lobule: Secondary somatosensory cortex

⑶ Somatosensory perception

① Proprioceptive sense (self-receptive sense), deep touch: Involves the primary somatosensory cortex

② Light touch and pain involve the lateral spinothalamic tract (lateral spinothalamic tract, lateral pathway)



4. Type 2. Nociceptors (pain receptors)



Input: 2019.03.02 23:15

Revised: 2022.04.24 12:11

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