Korean, Edit

NAME POSITION TITLE PROFIL
Jeongbin Park M.Sc.
Portrai Researcher
https://scholar.google.co.kr/
https://www.linkedin.com/ 

 

A. Educations and Trainings

 

INSTITUTION AND LOCATION DEGREE YEAR FIELD OF STUDY
Siheung Eunhaeng Middle School, Siheung, Republic of Korea   2010 ~ 2013 The president of the student (2012)
Gyeonggi-buk Science High School, Uijeongbu, Republic of Korea   2013 ~ 2015 Primarily focusing on Mathmatics and Science
Republic of Korea Air Force Soldier  Sergeant 2017 ~ 2019  
Seoul National University, Seoul, Republic of Korea B.S. 2015 ~ 2021 Biosystem Engineering (major), Economy (minor). GPA: 4.08 (total), 4.05 (major), 4.07 (minor) / 4.30. Summa Cum Laude
Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea M.Sc. 2021 ~ 2023 Molecular Medicine and Biopharmaceutical Sciences (major). GPA: 4.30 / 4.30

 

B. Careers

 

INSTITUTION AND LOCATION DURATION FIELD OF STUDY
Portrai, Inc. 21.09.01 ~ 24.08.30 Spatial Transcriptomics

 

C. Honors and Certificates

 

DURATION DESCRIPTIONS
2023.12.22 Korean Big Data Analyst; Certificate
2023.02.24 Master Degree Best Excellence Award
2021.04.15 ~ 11.25 Nano Young Challenge, The Award of Korean Nanotechnology Research Society
2021.08.20 Department of Nuclear Medicine, Seoul National University College of Medicine Research's Day Ideaton, Second-best Idea Award
2018.11.30 Korean Craftsman of Information Equipment Operation; Certificate
2018.06.01 Korean Industrial Engineer of Hazardous Material; Certificate
2018.05.25 Korean Industrial Engineer of Electricity; Certificate
2017.12.22 National Biotechnology Competition, Sponsored by Korean Chemical Engineering Association; Silver Prize
2017.12.01 Korean Industrial Engineer of Information Processing; Certificate
2016.11.23 National Cryptographic Contest; Special Award
2015.12.22 National Mathematics Competition for College Students; Gold Prize

 

D. Publications and Patents 

 

CATEGORY DESCRIPTIONS
Journal Lee, D., Park, J., Cook, S., Yoo, S. J., Lee, D., and Choi, H. (2024) IAMSAM : Image-based Analysis of Molecular signatures using the Segment-Anything Model. Genome Biology. co-first author. [Link] [App] [GitHub]
Journal Park, S., Park, J., Kim, J., Choi, H., Kim, I., Chung, E-J., and Kwon, J. (2024). Analysis of Unmapped RNA-seq Data from Cancer Spatial Transcriptome to Decipher Cancer Microbiome. bioRxiv. 2nd author. [Link] [GitHub]
Journal Choi, H., Park, J., Kim, S., Kim, J., Lee, D., Bae, S., Shin, H., and Lee, D. (2024). CELLama: Foundation Model for Single Cell and Spatial Transcriptomics by Cell Embedding Leveraging Language Model Abilities. bioRxiv. 2nd author. [Link] [GitHub]
Journal Ohn, J., Seo, M. K., Park, J., Lee, D., and Choi, H. (2024). SpatialSPM: Statistical parametric mapping for the comparison of gene expression pattern images in multiple spatial transcriptomic datasets. Nucleic Acids Research. 3rd author. [Link] [GitHub]
Journal Choi, T. H., Yoo, R. J., Park, J. Y., Kim, J. Y., Ann, Y. C., Park, J., ... and Lee, Y. S. (2024) Development of finely tuned liposome nanoplatform for macrophage depletion. Journal of Nanobiotechnology. 6th author. [Link]
Journal Park, J., Lee, D., Lee, J. E., Lee, D., Song, I. H., Park, H. S., ... and Im, H. J. (2024) A Spatial Transcriptomics based Label-Free Method for Assessment of Human Stem Cell Distribution and Effects in a Mouse Model of Lung Fibrosis. Advanced Therapeutics. 1st author. [Link]
Journal Park, J. et al. (2023). Magnetic resonance imaging-based quantification of endosomal escape using iron oxide nanoparticles-loaded lipid nanoparticles. Journal submitted. co-first author. [Link]
Journal Park, J., Cook, S., Lee, D., Choi, J., Yoo, S., Im, H. J., ... and Choi, H. (2023). Generation of Super-resolution Images from Barcode-based Spatial Transcriptomics Using Deep Image Prior. bioRxiv. 1st author. [Link] [GitHub]
Journal Oh, C., Lee, W., Park, J., Choi, J., Lee, S., Li, S., ... and Im, H. J. (2023). Development of Spleen Targeting H2S Donor Loaded Liposome for the Effective Systemic Immunomodulation and Treatment of Inflammatory Bowel Disease. ACS nano, 17(5), 4327-4345. 3rd author. [Link]
Journal Park, J., Choi, J.Y., Choi, H. & Im, H. J. (2022). Spatial Transcriptomics-based Identification of Molecular Markers for Nanomedicine Distribution in Cancer Tissue. Small Methods, 6(11), 2201091. co-first author. [Link]
Journal Park, H. R., Im, H. J., Park, J., Yoon, B. W., Lim, Y. H., Song, E. J., ... and Paek, S. H. (2022). Long-Term Outcomes of Bilateral Subthalamic Nucleus Deep Brain Stimulation for Patients With Parkinson's Disease: 10 Years and Beyond. Neurosurgery, 10-1227. 2022; 3rd author. [Link]
Journal Lee, H., Park, J., Im, H. J., Na, K. J., & Choi, H. (2021). Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients. Scientific reports, 11(1), 1-9; 2nd author. [Link]
Patent Lee, D., Park, J., Kook, S., Jeong, Y., Im, M., Lee, J., and Lee. D. Patent and Trademark Office, Republic of Korea. Application Number: 10-2024-0012396. Application Date: 2024.01.26. Registration Number: 10-2728909. Registration Date: 2024.11.07. An apparatus or a method for separation or analysis of core from spatial transcriptome and program stored in computer readable storage medium for executing the same. 2nd inventor.
Patent Choi, H., Im, H.-J., Park, J., and Lee, D. Patent and Trademark Office, Republic of Korea. Application Number: 10-2023-0060674. Application Date: 2023.05.10. Super resolution Spatial transcriptome image generating method, Apparatus performing the same, and Program recorded in computer readable media for performing the same. 3rd inventor.
Patent Park, J., Lee, J., Lee, D., and Lee, D. Patent and Trademark Office, Republic of Korea. Application Number: 10-2023-0048433 (preliminary), 10-2023-0104148. Application Date: 2023.04.12 (preliminary), 2023.08.09, Registration Number: 10-2718648, Registration Date: 2024.10.14. Exploring the Microscopic Distribution and Therapeutic Effects of Stem Cell Therapy for Lung Fibrosis using Spatial Transcriptomics; 1st inventor.
Patent Im, H.-J., Choi, H., Li, S., and Park, J. Patent and Trademark Office, Republic of Korea. Application Number: PCT/KR2023/004192. Application Date: 2023.03.29. A method of recommending target candidates of a cell cluster in cancer microenvironment by Single-cell transcriptome analysis, device, and program thereof; 4th inventor.
Patent Im, H.-J., Park, J., and Lee, S. Patent and Trademark Office, Republic of Korea. Application Number: 10-2022-0181667. Application Date: 2022.12.22. Method for analyzing endosomal escape efficiency of lipid nano particles; 2nd inventor.
Patent Im, H.-J., Park, J., and Lee, S. Patent and Trademark Office, Republic of Korea. Application Number: PCT/KR2022/021076. Application Date: 2022.12.22. Method for analyzing endosomal escape efficiency of lipid nano particles; 2nd inventor. [Link]
Patent Im, H.-J., Park, J., Choi, J., and Choi, H. Patent and Trademark Office, Republic of Korea. Application Number: 10-2022-0057185. Application Date: 2022.05.10. Registration Number: 10-2489146. Registration Date: 2023.01.11. A device, system, or computer program for finding molecular profiles related to tissue distribution of fluorescently labeled drugs using spatially resolved transcriptomics technology; 2nd inventor.
Patent Im, H.-J., Choi, H., Li, S., and Park, J. Patent and Trademark Office, Republic of Korea. Application Number: 10-2022-0038613. Application Date: 2022.03.29. A method of recommending target candidates of a cell cluster in cancer microenvironment by Single-cell transcriptome analysis, device, and program thereof; 4th inventor.
Patent Im, H.-J., Park, J., Choi, J., and Choi, H. Patent and Trademark Office, Republic of Korea. Application Number: 10-2022-0042378. Application Date: 2021.06.25. Registration Number: 10-2489145. Registration Date: 2023.01.11. A method for finding molecular profiles related to tissue distribution of fluorescently labeled drugs using spatially resolved transcriptomics technology; 2nd inventor.
Book Kim, S.K., Park, J.B. (2023) First to Tenth Steps in Statistics. FESTBOOK MEDIA. ISBN: 979-11-92302-33-1 (1st ed), 979-11-92302-44-7 (2nd ed), 979-11-92190-14-3 (3rd ed); 2nd author. [Link] [Kor] [Eng]
Book Park, J.B. (2022) Whole Life Science - Microscopic Understanding. FESTBOOK MEDIA. ISBN: 979-11-92302-81-2 (POD), 979-11-69291-13-2 (e-Book); 1st author. [Link] [Kor] [Eng]
Book Park, J.B., Lee, E.J. (2022) Organic Chemistry that You Want to Know. FESTBOOK MEDIA. ISBN: 979-11-92302-09-6 15430; 1st author. [Link] [Kor] [Eng]

 

E. Presentations

 

DURATION DESCRIPTIONS
2024.03.22 Choi, J. Y., Park, J., Lim, M., Lee, D., Lee, J. E., Choi, H., & Im, H.-J. (2024, March 22). Abstract 3481: Comparative spatial transcriptomic analysis of monoclonal antibodies targeting the same molecule: A comparison between cetuximab and panitumumab. Poster session presented at the annual meeting of the Cancer Research Society, published in Cancer Res, 84(6_Supplement), 3481. [Link]
2024.03.22 Lee, D., Park, J., Cook, S., Yoo, S., Lee, D., & Choi, H. (2024, March 22). Abstract 7431: IAMSAM: Image-based analysis of molecular signatures using the Segment-anything model - Integrative analysis tool for tumor microenvironment. Poster session presented at the annual meeting of the Cancer Research Society, published in Cancer Res, 84(6_Supplement), 7431. [Link]
2024.03.22 Park, J., Cook, S., Lee, D., Choi, J., Yoo, S., Im, H.-J., Lee, D., & Choi, H. (2024, March 22). Abstract 2329: Cancer region definition using spatial gene expression patterns by super resolution reconstruction algorithm for spatial transcriptomics data. Poster session presented at the annual meeting of the Cancer Research Society, published in Cancer Res, 84(6_Supplement), 2329. [Link]
2024.03.22 Park, J., Park, S. H., Lee, D., Lee, J. E., Lee, D., Na, K. J., Choi, H., & Im, H.-J. (2024, March 22). Abstract 4881: Detecting cancer microbiota using unmapped RNA reads on spatial transcriptomics. Poster session presented at the annual meeting of the Cancer Research Society, published in Cancer Res, 84(6_Supplement), 4881. [Link]
2023.01.10 Radiomedicine Webzine Interview Jan 2023: Spatial Transcriptomics-Based Identification of Molecular Markers for Nanomedicine Distribution in Tumor Tissue
2022.11.24 Spatial Transcriptomics-Based Identification of Molecular Markers for Nanomedicine Distribution in Tumor Tissue; Biology Research Information Center in Korea
2022.09.30 Korea iBRIC Interview : Spatial Transcriptomics-Based Identification of Molecular Markers for Nanomedicine Distribution in Tumor Tissue
2022.03.18 Discovery of Stromal Targets in Pancreatic Cancer; 2022 AACR Poster
2022.01.10 Korea Institute of Radiological & Medical Sciences Poster
2021.11.25 Nano Convergence Exhibition 2021 Presentation
2021.11.17 Nature Conference ‘Bio-Inspired Nanomaterials’ Short Talk
2021.11.15 ~ 17 Nature Conference ‘Bio-Inspired Nanomaterials’ Top 20 Teams Presentation
2021.07.07 ~ 09 Nano Korea 2021 Nanotechnology Convergence Exhibition Poster Session
2016.06.09 Capstone: Innovation on Wheelchair Soccer

 

F. Project Experiences 

 

DURATION DESCRIPTIONS
2023.10 ~ Present Quantification of Tumor-infiltrating Lymphocytes
2023.08 ~ Present Establishing a Methodology for Normalizing Image-based Spatial Transcriptomics
2023.08 ~ Present Project PortraiTME: Evaluating the Tumor Microenvironment through Digital Pathology
2023.04 ~ Present Systemic Immunity Evaluation of Liposomes Encapsulating H2S Donor for Mouse Inflammatory Bowel Disease Treatment through Multi-omics Study
2022.08 ~ Present Project Albani: Investigating the Accumulation Patterns in Liver and Tumor Based on Different Glycation Types of Albumin Nanoplatform
2022.03 ~ Present Project Craft: Crawling Public scRNA-seq and ST Data to Match Similar Datasets
2022.03 ~ Present SpatialSPM: Statistical parameteric mapping for the comparison of gene expression pattern images in multiple spatial transcriptomic datasets
2021.12 ~ Present Project SuperST: Development and Application of SuperResolution Algorithm Using Deep Image Prior
2023.05 ~ 2023.11 Automating Bioinformatics Downstream Analysis and Report Generation
2022.09 ~ 2023.11 A Spatial Transcriptomics based Label-Free Method for Assessment of Human Stem Cell Distribution and Effects in a Mouse Model of Lung Fibrosis
2020.05 ~ 2023.07 MR Imaging Based Evaluation of Endosomal Escape of Lipid Nanoparticles
2023.04 ~ 2023.05 IAMSAM : Image-based Analysis of Molecular signatures and the Segment-Anything Model
2023.02 ~ 2023.03 Finely Tuned Liposome Nanoplatform for Macrophage Depletion and Computational Evaluation of the Nanoplatform on Tissue
2022.12 ~ 2023.02 Comparison of Downstream Analysis of MERFISH and Visium Mouse Brain Samples
2022.12 ~ 2023.02 Identification of Lung Cancer-Specific TADs and Genes through Hi-C and ChIP-seq
2022.07 ~ 2023.01 Identification of Target Sites for CRISPR-Cas9 by Utilizing bulk RNA-seq, scRNA-seq, ST, Chip-seq, Hi-C seq, and Transcription Factor Databases for Prostate Cancer Therapy
2022.08 ~ 2022.12 Peptide-protein Simulation Using AlphaFold2 and PepNN
2022.11 ~ 2022.12 Gene Target Exploration in Various Disease Models
2022.09 ~ 2022.12 Training of CNN with VistoSeg-labeling for Cell Counting in Visium Dataset
2022.08 ~ 2022.12 Development of Spleen Targeting H2S Donor Loaded Liposome for the Effective Systemic Immunomodulation and Treatment of Inflammatory Bowel Disease
2021.08 ~ 2022.11 Spatial Transcriptomics-based Analysis of Paclitaxel-Nanogel’s Efficacy in Tumor Tissue
2020.01 ~ 2022.10 Spatial Transcriptomics-based Identification of Molecular Markers for Nanomedicine Distribution in Tumor Tissue (PortraiDRUG)
2021.07 ~ 2022.07 Spatial Transcriptomics-based Identification of Molecular Markers Related to Antibody Drug Conjugates
2022.05 ~ 2022.07
Spatial Transcriptomics to Identify the Spatial Distribution of Microbiome in Inflammatory Bowel Disease
2022.04 ~ 2022.05 Lipobot by using collagenase activity
2021.07 ~ 2022.04 Co-treatment of Magnetic Hyperthermal Iron Oxide and Temozolomide to Treat Glioblastoma
2021.11 ~ 2022.02 Development of Drug Matching Pipeline for Discovery of Co-drugs: Focusing on CLDN3(tentative) Antibody Primarily
2020.12 ~ 2021.05 Cancer Immunotherapy with GLUT1 Inhibition
2020.07 ~ 2021.02 Discovery of Potential Imaging and Therapeutic Targets for Severe Inflammation in COVID-19 Patients
2021.01 ~ 2021.01 Imaging Data Analysis on FDG-PET for Brown Adipose Tissue (BAT)
2020.03 ~ 2021.01 Graduation Thesis: Development of Algorithm for Classification of Korean Rice Seed Cultivars
2020.07 ~ 2020.07 Dopamine Transporter Imaging for the Estimation of Parkinson’s Disease
2020.04 ~ 2020.06 Application of Microprocessor Course: IoT Air Cleaner Linked with Web&App Application
2018.07 ~ 2018.07 Hackathone: DetecTrone for the Detection of CBR Situation
2017.07 ~ 2017.07 Invention Competition: Magnetic Resonance Imaging Instrument for Partial Body Use
2016.06 ~ 2016.06 Capstone: Innovation on Wheelchair Soccer
2016.03 ~ 2016.05 Google Science Fair: Realization of Kuhn’s AI Theory

 

G. Scholarship Information

 

PERIOD NAME SOURCE
2024.09 ~  $13,000 per year, up to 5 years since Sep, 2024 Korean Foundation for Advanced Studies (KFAS) Funding
2023.09 ~ Abandoned Government Fund (up to 2 years) National Institute for International Education (NIIED), Ministry of Foreign Affairs
2021.03 ~ 08 BK21 Four Scholarship Seoul National University Foundation
2020.09 ~ 02 Develop Fund Scholarship Seoul National University Foundation
2020.03 ~ 08 Develop Fund Scholarship Seoul National University Foundation
2017.03 ~ 08 National Scholarship Korea Student Aid Foundation; KOSAF
2016.09 ~ 02 National Scholarship Korea Student Aid Foundation; KOSAF
2016.03 ~ 08 GPA Scholarship Seoul National University
2015.09 ~ 02 National Scholarship Korea Student Aid Foundation; KOSAF
2015.03 ~ 08 National Scholarship Korea Student Aid Foundation; KOSAF

 

H. Skills and Techniques

 

CATEGORY DESCRIPTIONS
Experimental Techniques pH Meter, Iron Oxide Solvothermal Synthesis, Liposome Preparation, Lipid Nanoparticle (LNP) Preparation, Radioisotope Labeling, Dynamic Light Scattering (DLS), Zeta Potential, Microplate Reader, UV-Vis Spectrometer, Nanodrop, Fourier Transformation Infrared Spectrometer (FT-IR), Transmission Electron Microscope Sampling (TEM), Cryo-TEM, In vitro MR Imaging, Cell Culture, Cell Freezing and Thawing, Flow Cytometry, Confocal Imaging, Tomocube, MTT Assay, Lactate Assay, Bio-TEM Sampling, Live Cell Imaging with GFP Transfection, Tissue Fluorescence Microscope, Tumor Modeling, In vivo Imaging System (IVIS), Ex-vivo Imaging, Sacrifice, Tumor Molding with Optimal Cutting Temperature (OCT), Tissue Cryotome, In vivo MR Imaging, PET Imaging
Applicable Programming Languages C/C++, Java, RStudio, Python, HTML, Javascript, Processing, Verilog, Arduino, Linux
Others Computer-aided Design (CAD) using SolidWorks or Inventor, 3D Printing, Circuit Design, IoT Realization, Website Management

 

I. Courseworks

 

CATEGORY DESCRIPTIONS
Graduate School Courses for Master Process Clinical Proteomics(ENG), Molecular Imaging and Nanomedicine(ENG), Theranostics and Precision Medicine, Principles and Practice of Drug Development, Principles and Application of Data Science, Radionanomedicine Seminar, Graduate School Thesis Research
Undergraduate School Courses for General Calculus 1, Physics, Understanding Popular Arts, Philosophical Understanding of Science, North Korean Studies, Introduction to Psychology, Biology, English Foundations(ENG), College Writing: Process & Structure, College English 1(ENG), Calculus 2, Biology Lab., Introduction to the Performing Arts, Quantum Theory and Human Civilization, Freshman Seminars, Weight Training, Introduction to Electrical and Computer Engineering, Innovative Capstone Design 2, Elementary Spanish 1, Computer Engineering Seminar, Logic Design(ENG), Structure and Function of Human Brain, Physics Lab., Chemistry, Bicycle and Sports Science, Computer Programming(ENG)
Undergraduate School Courses for Major Introduction to Biosystems & Biomaterials Science and Engineering, Introduction to Computer Programming, Material Engineering for Biological Application, Biology for Biosystems Engineering, Heat and Mass Transfer in Bioproducts(ENG), Applied Mathematics 1, Dynamics, Fluid Mechanics and Machinery(ENG), Bio-thermodynamics, Applied Engineering Mathematics 2, Organic Chemistry(ENG), Introduction to Statistics and Lab., Application of Electrical and Electronics Engineering and Lab., Post-Harvest Process Engineering and Lab., Biomechanics and Lab., Engineering Properties of Bioproducts and Lab.(ENG), Experiments for Biosystems, Biosystems Control and Lab., Microprocessor Application, Practice in Biosystems Engineering, Seminar in Biosystems Engineering
Undergraduate School Courses for Minor Introductory Statistics for Economists, Econometrics(ENG), Microeconomics(ENG), Mathematics for Economics, Economic History, Principles of Economics 1, Macroeconomics

 

J. Reference

Contact: nate9389@gmail.com



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